FINAL PROJECT PROPOSAL: Magnus Opus and Exigence > Intensive vs. Conventional Insulin Therapy: An Analysis

Context- Type–1 diabetes is a chronic autoimmune disorder that affects an estimated 3 million Americans. Currently, no cure is available. However, insulin administration is offered as a means to stabilize blood glucose levels in an attempt to make the disease manageable.
Scientists and healthcare providers differ over the amount of insulin that patients should receive. Currently, two predominating strategies of insulin administration exist: intensive insulin therapy and conventional insulin therapy. Intensive therapy, calls for higher doses of insulin resulting in strict glycemic control, while conventional therapy advocates for lower doses of insulin resulting in a looser glycemic control. The core of this debate resides in the health risks associated with each of these therapies. Proponents of intensive insulin therapy argue that intensive therapy is a better long-term solution with regards to microvascular diseases that arise as a complication of diabetes. However, those who oppose intensive therapy and support conventional, site that dangerous complications can result from an accidental overdose of insulin.


Purpose: To carefully analyze and present the most prevalent research regarding insulin therapy. This analysis should serve as a relatable document, of which doctors and clinicians can better understand which insulin therapy might be best for each individual case of diabetes.

Audience- Clinicians, patients, researchers, loved one of patients, and people who are just interested in learning more about the debate regarding intensive vs. conventional insulin therapy.
April 8, 2015 | Unregistered CommenterJoseph Frankel
J -- you will either need to select one audience OR divide the document into one portion for clinician review and the other portion a patient handout. Do you want to use the divided but companion document approach?

I caution you to not fall into the trap of one approach or the other. Is there a middle path? Might the path of loose or tight change over time?

Finally, what about diet as a "medicine"? You can look at the sophisticated patient blogs of Jenny in Diabetes 101 and science journalist David Gonzalez. While they are not type 1, their approach to low carb eating and stepped-up monitoring is very compelling. You can ask me about what I do....

Good project for you as you head off to M.S. in the fall.
April 9, 2015 | Registered CommenterMarybeth Shea